An undiagnosed TSH-secreting pituitary macroadenoma found during pregnancy

TSH-Secreting Pituitary Macroadenoma in a Girl with Lingual Thyroid

Patients with long-standing hypothyroid are, in some cases, reported to develop pituitary gland hyperplasia due to loss of feedback inhibition of thyroxine in hypothalamus-the condition of which typically regresses after thyroxine replacement. Herein, a 15-year-old girl-with long-standing untreated lingual hypothyroid-presents with a pathologically proven TSH pituitary macroadenoma and bilatera...

A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome

Growth of Pituitary Tumors Secreting TSH*

Destruction of the thyroid gland by I's' in mice is followed by the development of TSH (thyroid stimulating hormone)-secreting pituitary tumors (5, 11, 13). These tumors can at first be grafted only on mice similarly radiothyroidectomized and not on normal animals (5) ; thus, they are initially conditioned or dependent growths. The tumor cells gain autonomy in the course of passages, as mdi cat...

A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome

FSH-secreting pituitary adenomas can affect sexual and reproductive function. In this article, we have reported the case of a 32-year-old male with secondary infertility. The patient had sexual and reproductive disturbances. The test results of the blood samples indicated obviously decreased testosterone (T) and estradiol (E2) levels. Based on previous hormonal results, the patient received pit...

Dense calcification in a GH-secreting pituitary macroadenoma

UNLABELLED A 30-year-old female presented with a history of secondary amenorrhoea, acromegalic features and progressive visual deterioration. She had elevated serum IGF1 levels and unsuppressed GH levels after an oral glucose tolerance test. Magnetic resonance imaging revealed a heterogeneously enhancing space-occupying lesion with atypical extensive calcification within the sellar and suprasel...